Document Detail


Nucleic acid-induced aggregation and pyrene excimer formation.
MedLine Citation:
PMID:  19722507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nucleic acid was found to induce the aggregation of the positively charged pyrene probe (compound 1); as a result, strong pyrene excimer emission was observed. The intensity of the excimer emission was dependent on the concentration of the pyrene probe and the oligonucleotide length, sequence, and concentration. These results suggest a new strategy for label-free nucleic acid-based biosensing applications.
Authors:
Ruixing Zhang; Dan Tang; Ping Lu; Xiangyu Yang; Dongli Liao; Yujing Zhang; Mingjun Zhang; Cong Yu; Vivian W W Yam
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Organic letters     Volume:  11     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-24     Completed Date:  2009-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4302-5     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
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MeSH Terms
Descriptor/Qualifier:
Fluorescent Dyes / chemical synthesis,  chemistry*
Molecular Structure
Nucleic Acids / chemistry*
Pyrenes / chemical synthesis,  chemistry*
Chemical
Reg. No./Substance:
0/Fluorescent Dyes; 0/Nucleic Acids; 0/Pyrenes; 129-00-0/pyrene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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