| Nucleic acid encoding to program self-assembly in chemical biology. | |
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MedLine Citation:
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PMID: 18568159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This tutorial review serves as an introduction to the use of oligonucleotides and in particular peptide nucleic acids (PNAs) to encode function beyond heredity. Applications in chemical biology are reviewed starting with the use of nucleic acid tags to program self-assembled microarrays of small and macromolecules, followed by the use of nucleic acid templated reactions for the purpose of DNA or RNA sensing and finally, the use of nucleic acid templates to display ligands. |
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Authors:
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Zbigniew L Pianowski; Nicolas Winssinger |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2008-04-17 |
Journal Detail:
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Title: Chemical Society reviews Volume: 37 ISSN: 0306-0012 ISO Abbreviation: Chem Soc Rev Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-23 Completed Date: 2008-09-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0335405 Medline TA: Chem Soc Rev Country: England |
Other Details:
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Languages: eng Pagination: 1330-6 Citation Subset: IM |
Affiliation:
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Organic and Bioorganic Chemistry Laboratory, Institut de Science et Ingénierie Supramoléculaires, Université Louis Pasteur, 8 allée Gaspard Monge, Strasbourg, 67000. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Binding Sites Combinatorial Chemistry Techniques / methods* DNA / chemistry, genetics, metabolism Genetic Code* Ligands Microarray Analysis / methods* Nucleic Acid Conformation Oligonucleotides / chemistry, genetics*, metabolism Peptide Nucleic Acids / chemistry, genetics*, metabolism RNA / chemistry, genetics, metabolism Templates, Genetic |
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Reg. No./Substance:
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0/Ligands; 0/Oligonucleotides; 0/Peptide Nucleic Acids; 63231-63-0/RNA; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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