| Nucleic acid based biosensors: the desires of the user. | |
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MedLine Citation:
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PMID: 16019267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The need for nucleic acid based diagnostic tests has increased enormously in the last few years. On the one hand, this has been stimulated by the discovery of new hereditary genetic disease loci following the completion of the Human Genome Project, but also by the presence of new rapidly spreading viral threats, such as that of the SARS epidemic, or even micro-organisms released for the purpose of biological warfare. As in many instances rapid diagnoses of specific target genetic loci is required, new strategies have to be developed, which will allow this to be achieved directly at the point-of-care setting. One of these avenues being explored is that of biosensors. In this review, we provide an overview of the current state of the art concerning the high-throughput analysis of nucleic acids, and address future requirements, which will hopefully be met by new biosensor-based developments. |
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Authors:
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Sinuhe Hahn; Susanne Mergenthaler; Bernhard Zimmermann; Wolfgang Holzgreve |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Bioelectrochemistry (Amsterdam, Netherlands) Volume: 67 ISSN: 1567-5394 ISO Abbreviation: Bioelectrochemistry Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-08-26 Completed Date: 2005-11-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100953583 Medline TA: Bioelectrochemistry Country: Netherlands |
Other Details:
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Languages: eng Pagination: 151-4 Citation Subset: IM |
Affiliation:
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Laboratory for Prenatal Medicine, University Women's Hospital/Department of Research, University of Basel, Spitalstrasse 21, CH 4031 Basel, Switzerland. shahn@unbs.ch |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biosensing Techniques
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trends* Nucleic Acids / analysis* Oligonucleotide Array Sequence Analysis / trends* Polymerase Chain Reaction |
| Chemical | |
Reg. No./Substance:
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0/Nucleic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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