Document Detail

Nuclear texture during the cell cycle in acute lymphoid leukemia.
MedLine Citation:
PMID:  8218977     Owner:  NLM     Status:  MEDLINE    
Description of morphological and textural changes during cell cycle were studied in 31 diploid Acute Lymphoid Leukemia ALL cases. Feulgen stained nuclei were measured by image analysis. Cells with 2C, 3C and 4C content of DNA were considered as being in G1, S and G2 phase of cell cycle respectively. The main observed transformations associated with cell cycle were continuous increases in nuclear size and in quantities of black/white chromatin clumps and points. An overall correct classification of 92.5% was achieved by multivariate data analysis. However, significant differences between A L L cases were noticed.
C Souchier; A M Manel; M Ffrench; D Treilleritouet; P A Bryon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  In vivo (Athens, Greece)     Volume:  7     ISSN:  0258-851X     ISO Abbreviation:  In Vivo     Publication Date:    1993 Jul-Aug
Date Detail:
Created Date:  1993-12-10     Completed Date:  1993-12-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8806809     Medline TA:  In Vivo     Country:  GREECE    
Other Details:
Languages:  eng     Pagination:  339-42     Citation Subset:  IM    
Cytologie Analytique, Lyon, France.
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MeSH Terms
Cell Cycle / physiology*
Cell Nucleus / ultrastructure*
Hematopoietic Stem Cells / pathology
Image Processing, Computer-Assisted
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics,  pathology*

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