Document Detail

Nuclear techniques in ischemic heart disease.
MedLine Citation:
PMID:  7064808     Owner:  NLM     Status:  MEDLINE    
Until recently, it was necessary to measure parameters such as ventricular pressure to assess the effects of drugs on the force of myocardial contraction--the inotropic effect. Even simpler measurements such as cardiac output are not completely satisfactory, because they are determined not only by the contractile state but also by the diastolic volume of the ventricles, outflow impedance, and heart rate. Within the past few years, the use of radioactive tracer techniques has made it possible to measure the changes in ventricular volume that occur throughout the cardiac cycle. With these techniques, it is now possible to measure end-diastolic and end-systolic volumes, the rates of ventricular emptying and filling, stroke volume, and systolic and diastolic time intervals. In complicated diseases such as combined valvular and coronary artery disease the ventricular response to antiarrhythmic, vasodilator, and inotropic drugs can be assessed in individual patients.
H N Wagner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  103     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-05-27     Completed Date:  1982-05-27     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  681-8     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiac Output
Coronary Disease / radionuclide imaging*
Heart / radionuclide imaging*
Heart Auscultation / instrumentation
Heart Ventricles
Myocardial Contraction
Stroke Volume

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