| Nuclear morphometry in canine acanthomatous ameloblastomas and squamous cell carcinomas. | |
| | |
MedLine Citation:
|
PMID: 16864123 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of this study was to evaluate whether morphometrical analysis can be of diagnostic value for canine acanthomatous ameloblastoma. We calculated, by means of an automated image analyser, some morphometric nuclear parameters, in particular: mean nuclear area (MNA), mean nuclear perimeter (MNP), maximum and minimum diameters (MDx and MDm) coefficient of variation of the nuclear area (NACV), largest to smallest dimension ratio (LS ratio), and form factor (FF), in 8 canine acanthomatous ameloblastomas, and we compared these morphometric data to those of 13 squamous cell carcinomas of canine gingiva. The results indicated a progressive increase of the MNA, NACV, MNP and MDm proceeding from acanthomatous ameloblastomas (MNA: 42.11+/-8.74; NACV: 28,36+/-7,23; MNP: 24.18+/- 2.68; MDm: 5.69+/-0.49) to squamous cell carcinomas (MNA:49,69+/-9,10; NACV: 30,89+/-7,75; MNP: 25.63+/-2.54; MDm: 6.64+/-0.73). On the contrary, the LS ratio and the FF resulted greater in acanthomatous ameloblastomas (LS ratio: 1,63+/-0,12; FF: 1,13+/-0,002) than in SCCs (LS ratio: 1,40+/-0,12; FF:0.91+/-0.38). Moreover, the MNA, MNP,MDx and MDm resulted similar (MNA: p=0.89; MNP: p=0,65; MDm: p=0,16; MDx: p=0,13) in a subset of four acanthomatous ameloblastomas with cellular atypia (MNA:49,01+/-6,88; MNP: 26,28+/-1,99; MDm: 6.08+/-0.41; MDx: 10.18+/-0.88) and in squamous cell carcinomas (MNA:49.69+/-9,10; MNP: 25.63+/-2.54; MDm: 6.64+/-0.73; MDx: 9.26+/-1.05). While the NACV values resulted higher in typical acanthomatous ameloblastoma (29,99+/-6,06) than in atypical acanthomatous ameloblastoma (26,74+/-8,84) and similar to those of the SCCs (30,89+/-7,75). These results seem to confirm that acanthomatous ameloblastoma is a malignant or potentially malignant lesion and emphasizes that nuclear morphometry analysis can be an useful diagnostic and prognostic method in canine oral pathology. |
| | |
Authors:
|
M Martano; S Damiano; B Restucci; O Paciello; V Russo; P Maiolino |
Related Documents
:
|
12113213 - The utility of the state-trait anger expression inventory with offenders. 923543 - Radiological protection in equine radiography and radiotherapy. 15942433 - Probiotics for the developing world. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of histochemistry : EJH Volume: 50 ISSN: 1121-760X ISO Abbreviation: Eur J Histochem Publication Date: 2006 Apr-Jun |
Date Detail:
|
Created Date: 2006-07-25 Completed Date: 2007-01-12 Revised Date: 2008-08-15 |
Medline Journal Info:
|
Nlm Unique ID: 9207930 Medline TA: Eur J Histochem Country: Italy |
Other Details:
|
Languages: eng Pagination: 125-30 Citation Subset: IM |
Affiliation:
|
Dipartimento di Patologia e Sanità Animale, Facoltà di Scienze Biotecnologiche, Università degli Studi di Napoli Federico II, Naples, Italy. manuela.martano@unina.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Ameloblastoma
/
diagnosis,
pathology,
veterinary* Animals Carcinoma, Squamous Cell / diagnosis, pathology, veterinary* Cell Nucleus / pathology*, ultrastructure Dog Diseases / diagnosis*, pathology Dogs Gingiva / pathology*, ultrastructure Image Cytometry / methods Jaw Neoplasms / diagnosis, pathology, veterinary* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: On the nucleolar size and density in human early granulocytic progenitors, myeloblasts.
Next Document: Cytomegalovirus and BK-Virus co-infection of a clinically non-functioning adrenal adenoma: innocent ...