Document Detail

Nuclear envelope dynamics in oocytes: from germinal vesicle breakdown to mitosis.
MedLine Citation:
PMID:  12517709     Owner:  NLM     Status:  MEDLINE    
We have recently gained new insight into the mechanisms involved in nuclear envelope breakdown, the irreversible step that commits a cell to the M phase. Results from mammalian cell and starfish oocyte studies suggest that mechanical forces of the cytoskeleton, as well as biochemical disassembly of nuclear envelope protein complexes, play important roles in this process.
Péter Lénárt; Jan Ellenberg
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in cell biology     Volume:  15     ISSN:  0955-0674     ISO Abbreviation:  Curr. Opin. Cell Biol.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-01-08     Completed Date:  2003-08-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8913428     Medline TA:  Curr Opin Cell Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  88-95     Citation Subset:  IM    
Gene Expression and Cell Biology/Biophysics Programmes, European Molecular Biology Laboratory, D-69117, Heidelberg, Germany.
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MeSH Terms
Cell Differentiation / physiology*
Cell Division / physiology*
Cell Size / physiology
Fertilization / physiology
Models, Biological
Nuclear Envelope / metabolism*,  ultrastructure
Oocytes / metabolism*,  ultrastructure

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