Document Detail

Nuclear 3,5,3'-triiodothyronine receptors in skeletal muscle of normal and small-for-gestational age newborn piglets.
MedLine Citation:
PMID:  2076448     Owner:  NLM     Status:  MEDLINE    
The number of nuclear T3 receptors in the longissimus dorsi muscle has been determined in normal and runt (intrauterine growth-retarded) newborn piglets. Values of maximal binding capacity (Bmax), as calculated by Scatchard analysis, were 48.2 +/- 4.3 and 39.7 +/- 4.7 mol X 10(-14).mg DNA-1 (mean values +/- SEM) for controls and runts respectively (p less than 0.01; n = 13 pairs of littermates). The lower Bmax in the runts may help to explain their reduced metabolic rate and lower respiratory enzyme activities in skeletal muscle, compared with controls of normal birth weight.
M J Dauncey; R Geers
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biology of the neonate     Volume:  58     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1990  
Date Detail:
Created Date:  1991-04-22     Completed Date:  1991-04-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  291-5     Citation Subset:  IM    
Department of Cell Biology, AFRC Institute of Animal Physiology and Genetics Research, Cambridge, UK.
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MeSH Terms
Animals, Newborn
Body Weight
Cell Nucleus / metabolism*
Muscles / anatomy & histology,  metabolism*
Organ Size
Receptors, Thyroid Hormone / metabolism*
Reference Values
Reg. No./Substance:
0/Receptors, Thyroid Hormone

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