Document Detail

Novel trends in celiac disease.
MedLine Citation:
PMID:  21278765     Owner:  NLM     Status:  MEDLINE    
Celiac disease (CD) is one of the most common food intolerances in developed world. It affects genetically susceptible individuals and has severe consequences if it remains undiagnosed. A disease known for more than a century, it is still the focus for experts from various fields of research and development. Geneticists, pathologists, immunologists, food engineers and dieticians share their knowledge and expertise to improve the conditions of CD patients. With new insights in the pathomechanism of gluten processing and antigen presentation in CD, it was possible to improve the diagnostic antigen mimicking the primary epitope in CD. These celiac neo-epitopes are comprised of a complex of gliadin peptides crosslinked with transglutaminase (tTg). They are an early diagnostic marker for CD which occurs up to 6 months earlier than classical markers known to miss a certain amount of CD patients.
Torsten Matthias; Sandra Neidhöfer; Sascha Pfeiffer; Kai Prager; Sandra Reuter; M Eric Gershwin
Related Documents :
22719945 - Investigation of the plasmodium falciparum food vacuole through inducible expression of...
8582015 - Amino acids and peptides. xxv. preparation of fibronectin-related peptide poly(ethylene...
23697335 - Growth of listeria monocytogenes in refrigerated ready-to-eat foods in japan.
21111125 - Nutritional deficiencies in the developing world: current status and opportunities for ...
150265 - Hypersensitivity reactions to food colours with special reference to the natural colour...
9875365 - Shaping of the cat paw for food taking and object manipulation: an x-ray analysis.
Publication Detail:
Type:  Journal Article; Review     Date:  2011-01-31
Journal Detail:
Title:  Cellular & molecular immunology     Volume:  8     ISSN:  2042-0226     ISO Abbreviation:  Cell. Mol. Immunol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-08     Completed Date:  2011-07-26     Revised Date:  2014-09-20    
Medline Journal Info:
Nlm Unique ID:  101242872     Medline TA:  Cell Mol Immunol     Country:  China    
Other Details:
Languages:  eng     Pagination:  121-5     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Celiac Disease / diagnosis,  epidemiology,  etiology,  pathology*
Decision Making

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Immunostimulation in the era of the metagenome.
Next Document:  The epigenetics of autoimmunity.