| Novel therapeutic strategies for large vessel vasculitis. | |
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MedLine Citation:
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PMID: 16504829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Giant cell arteritis and Takayasu's arteritis are systemic vasculitides that cause inflammation of large arteries and their branches. Both have similar histology, but differ in their age of onset. Corticosteroids have been the mainstay of treatment for the past 50 years but are limited by the potential toxicity that may occur in almost 60% of patients. This limitation has lead to the investigation of alternative agents for the treatment of these diseases. |
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Authors:
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Curry L Koening; Carol A Langford |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Rheumatic diseases clinics of North America Volume: 32 ISSN: 0889-857X ISO Abbreviation: Rheum. Dis. Clin. North Am. Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-02-28 Completed Date: 2006-05-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8708093 Medline TA: Rheum Dis Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 173-86, xi Citation Subset: IM |
Affiliation:
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Center for Vasculitis Care and Research, Department of Rheumatic and Immunologic Diseases, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Inflammatory Agents
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therapeutic use Giant Cell Arteritis / therapy* Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Immunologic Factors / therapeutic use Immunosuppressive Agents / therapeutic use Platelet Aggregation Inhibitors / therapeutic use Takayasu Arteritis / therapy* Vascular Surgical Procedures |
| Grant Support | |
ID/Acronym/Agency:
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1 U54 RR019497-01/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Immunologic Factors; 0/Immunosuppressive Agents; 0/Platelet Aggregation Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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