Document Detail


Novel technique for ST-T interval characterization in patients with acute myocardial ischemia.
MedLine Citation:
PMID:  24832353     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: The novel signal processing techniques have allowed and improved the use of vectorcardiography (VCG) to diagnose and characterize myocardial ischemia. Herein, we studied vectorcardiographic dynamic changes of ventricular repolarization in 80 patients before (control) and during Percutaneous Transluminal Coronary Angioplasty (PTCA).
METHODS: We propose four vectorcardiographic ST-T parameters, i.e., (a) ST Vector Magnitude Area (aSTVM); (b) T-wave Vector Magnitude Area (aTVM); (c) ST-T Vector Magnitude Difference (ST-TVD), and (d) T-wave Vector Magnitude Difference (TVD). For comparison, the conventional ST-Change Vector Magnitude (STCVM) and Spatial Ventricular Gradient (SVG) were also calculated.
RESULTS: Our results indicate that several vectorcardiographic parameters show significant differences (p-value<0.05) before starting and during PTCA. Statistical minute-by-minute PTCA comparison against the control situation showed that ischemic monitoring reached a sensitivity=90.5% and a specificity=92.6% at the 5th minute of the PTCA, when aSTVM and ST-TVD were used as classifiers.
CONCLUSIONS: We conclude that the sensitivity and specificity for acute ischemia monitoring could be increased with the use of only two vectorcardiographic parameters. Hence, the proposed technique based on vectorcardiography could be used in addition to the conventional ST-T analysis for better monitoring of ischemic patients.
Authors:
Raúl Correa; Pedro David Arini; Lorena Sabrina Correa; Max Valentinuzzi; Eric Laciar
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-23
Journal Detail:
Title:  Computers in biology and medicine     Volume:  50C     ISSN:  1879-0534     ISO Abbreviation:  Comput. Biol. Med.     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-5-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1250250     Medline TA:  Comput Biol Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  49-55     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Ltd. All rights reserved.
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