Document Detail


Novel single nucleotide polymorphisms of bovine SREBP1 gene is association with fatty acid composition and marbling score in commercial Korean cattle (Hanwoo).
MedLine Citation:
PMID:  23065270     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The sterol regulatory element binding factor 1 (SREBP1) gene plays an important role in the biosynthesis of fatty acids. The aim of this study was to investigate the association between SNPs within SREBP1 gene and fatty acid composition of muscle fat and marbling score in a commercial population of Korean cattle. Among 10 SNPs in dbSNP of bovine SREBP1 gene, we identified 7 polymorphic SNPs and 84-bp ins/del variation (SREBP1-INT5 SNP) in commercial Korean cattle (n = 513). The SREBP1-9 SNP showed a significant effect on marbling score, monounsaturated fatty acids and C18:1n-9 in the muscle fat of commercial Korean cattle. However, SREBP1-INT5 SNP showed no effect on any fatty acid composition. Therefore, two polymorphisms in SREBP1 may improve flavored beef and meat quality in commercial Korean cattle.
Authors:
Yoonseok Lee; Dongyep Oh; Jeayoung Lee; Boomi La; Jungsou Yeo
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-14
Journal Detail:
Title:  Molecular biology reports     Volume:  -     ISSN:  1573-4978     ISO Abbreviation:  Mol. Biol. Rep.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0403234     Medline TA:  Mol Biol Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Charmpoom Hanwoo Research Institution, Charmpoom Hanwoo Co., Ltd., Chilgok-gun, Gyeongsangbuk-do, 718-913, South Korea, yoonseok95@ynu.ac.kr.
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