Document Detail


Novel prenylated bichalcone and chalcone from Humulus lupulus and their QR induction activities.
MedLine Citation:
PMID:  24397993     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A new prenylated chalcone xanthohumol M (1), a novel prenylated bichalcone humulusol (2) and six known chalcones (3-8) were found from Humulus lupulus. Their structures were determined by spectroscopic methods. All the chalcones' electrophilic abilities were assessed by GSH (glutathione) rapid screening, and their QR (Quinone reductase) induction activities were evaluated using hepa 1c1c7 cells. The results of electrophilic assay and QR induction activity assay consist quite well. New compounds 1 and 2, along with some known prenylated chalcones, displayed certain QR induction activity.
Authors:
Liyan Yu; Fuxian Zhang; Zhijuan Hu; Hui Ding; Huifang Tang; Zhongjun Ma; Xiaofeng Zhao
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-1-4
Journal Detail:
Title:  Fitoterapia     Volume:  -     ISSN:  1873-6971     ISO Abbreviation:  Fitoterapia     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-1-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  16930290R     Medline TA:  Fitoterapia     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013. Published by Elsevier B.V.
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