Document Detail

Novel polymeric solid-phase extraction material for complex biological matrices. Portable and disposable artificial kidney.
MedLine Citation:
PMID:  9061487     Owner:  NLM     Status:  MEDLINE    
The replacement of conventional hemodialysis treatment for a patient with malfunctioning kidneys by providing him/her with a portable and disposable "artificial kidney" which is connected to implanted artery and veneous cannulas on a patient's wrist is discussed. During a continuous flow of blood, plasma diffuses through a plasmapheretic membrane, passes through a bed of plasmacompatible sorbent Styrosorb, and arrives at an ultrafiltration membrane. Vacuum-operated ultrafiltration removes excess water together with dissolved urea and other small molecules, and Stryosorb removes medium-sized toxic substances. The hemocompatibility of the sorbent is improved by chemical modification of the surface.
V A Davankov; L A Pavlova; M P Tsyurupa; D R Tur
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of chromatography. B, Biomedical sciences and applications     Volume:  689     ISSN:  1387-2273     ISO Abbreviation:  J. Chromatogr. B Biomed. Sci. Appl.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-07-08     Completed Date:  1997-07-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9714109     Medline TA:  J Chromatogr B Biomed Sci Appl     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  117-22     Citation Subset:  IM    
Institute of Organo-Element Compounds, Russian Academy of Sciences, Moscow, Russia.
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MeSH Terms
Biocompatible Materials*
Hemofiltration / methods*
Kidney, Artificial*
Polystyrenes / therapeutic use*
Renal Dialysis
Reg. No./Substance:
0/Biocompatible Materials; 0/Polystyrenes

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