| Novel parameter for the diagnosis of distal middle cerebral artery stenosis with transcranial Doppler sonography. | |
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MedLine Citation:
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PMID: 20533446 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Transcranial Doppler sonography (TCD) is commonly used for the diagnosis of middle cerebral artery (MCA) stenosis. However, TCD indices to predict distal MCA (M2) stenosis have not yet been established. We compared TCD and magnetic resonance angiography (MRA) to validate a new index for the diagnosis of M2 stenosis. METHODS: Consecutive patients who underwent TCD and MRA were included. Based on MRA, M2 stenosis was defined as >50% narrowing beyond the bifurcation area. TCD index of the M2/M1 ratio was defined as the ratio between the mean flow velocity (MFV) obtained at a depth of 30-44 mm (M2) and a depth of 45-65 mm (M1). Sensitivity and specificity of the M2/M1 ratio were calculated from the receiver operating characteristic curve. The diagnostic yield of elevated MFV (>80 cm/s) and asymmetry index of >30% for M2 stenosis were also investigated. RESULTS: Among the consecutive patients, 105 with M2 stenosis were compared with 123 without MCA stenosis. The M2/M1 ratio was significantly higher in the M2 stenosis group (1.10 versus 0.86, p < 0.001). Sensitivity and specificity for M2 stenosis were most satisfying when the M2/M1 ratio of 0.97 was adopted as the cutoff value. Diagnostic yield of the M2/M1 ratio was better than MFV or asymmetry index. CONCLUSIONS: The M2/M1 ratio may be a highly specific parameter for assessing M2 stenosis with TCD. |
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Authors:
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Suk-Won Ahn; Sang-Soon Park; Yong-Seok Lee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of clinical ultrasound : JCU Volume: 38 ISSN: 1097-0096 ISO Abbreviation: J Clin Ultrasound Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-27 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401663 Medline TA: J Clin Ultrasound Country: United States |
Other Details:
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Languages: eng Pagination: 420-5 Citation Subset: IM |
Copyright Information:
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© 2010 Wiley Periodicals, Inc. |
Affiliation:
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Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Arterial Diseases
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ultrasonography* Constriction, Pathologic / ultrasonography* Female Humans Male Middle Aged Middle Cerebral Artery / ultrasonography* Sensitivity and Specificity Ultrasonography, Doppler, Transcranial* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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