| Novel cutaneous uses for botulinum toxin type A. | |
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MedLine Citation:
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PMID: 17177750 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Botulinum toxin type A is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It has been used extensively in the field of dermatology for the treatment of dynamic rhytides and in the treatment of hyperhidrosis. Botulinum toxin has an excellent safety profile and few side effects when used for these purposes. Recently, botulinum toxin has also been used experimentally in a number of other dermatologic conditions with good results. These conditions include: persistent facial flushing, gustatory sweating and epiphora, anal fissures, familial benign pemphigus (Hailey-Hailey disease), dyshidrotic eczema, and following surgical wound closures. While randomized, controlled prospective trials are still needed to further understand the efficacy and safety of botulinum toxin in these conditions, anecdotal and case report data suggest that botulinum toxin is both safe and efficacious in these and many other procedures. |
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Authors:
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Cheryl Bansal; Kenny J Omlin; Christine M Hayes; Thomas E Rohrer |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of cosmetic dermatology Volume: 5 ISSN: 1473-2165 ISO Abbreviation: J Cosmet Dermatol Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-12-20 Completed Date: 2008-05-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101130964 Medline TA: J Cosmet Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 268-72 Citation Subset: IM |
Affiliation:
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Drexel University College of Medicine, Philadelphia, PA 19144, USA. cb59@drexel.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Cutaneous Botulinum Toxin Type A / administration & dosage, therapeutic use* Humans Neuromuscular Agents / administration & dosage, therapeutic use* Skin Diseases / drug therapy* Wound Healing |
| Chemical | |
Reg. No./Substance:
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0/Botulinum Toxin Type A; 0/Neuromuscular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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