Document Detail


Novel cutaneous uses for botulinum toxin type A.
MedLine Citation:
PMID:  17177750     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Botulinum toxin type A is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It has been used extensively in the field of dermatology for the treatment of dynamic rhytides and in the treatment of hyperhidrosis. Botulinum toxin has an excellent safety profile and few side effects when used for these purposes. Recently, botulinum toxin has also been used experimentally in a number of other dermatologic conditions with good results. These conditions include: persistent facial flushing, gustatory sweating and epiphora, anal fissures, familial benign pemphigus (Hailey-Hailey disease), dyshidrotic eczema, and following surgical wound closures. While randomized, controlled prospective trials are still needed to further understand the efficacy and safety of botulinum toxin in these conditions, anecdotal and case report data suggest that botulinum toxin is both safe and efficacious in these and many other procedures.
Authors:
Cheryl Bansal; Kenny J Omlin; Christine M Hayes; Thomas E Rohrer
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of cosmetic dermatology     Volume:  5     ISSN:  1473-2165     ISO Abbreviation:  J Cosmet Dermatol     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-12-20     Completed Date:  2008-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130964     Medline TA:  J Cosmet Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  268-72     Citation Subset:  IM    
Affiliation:
Drexel University College of Medicine, Philadelphia, PA 19144, USA. cb59@drexel.edu
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MeSH Terms
Descriptor/Qualifier:
Administration, Cutaneous
Botulinum Toxin Type A / administration & dosage,  therapeutic use*
Humans
Neuromuscular Agents / administration & dosage,  therapeutic use*
Skin Diseases / drug therapy*
Wound Healing
Chemical
Reg. No./Substance:
0/Botulinum Toxin Type A; 0/Neuromuscular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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