Document Detail


Novel biomarkers in heart failure: an overview.
MedLine Citation:
PMID:  20477516     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Heart failure is a complex systemic syndrome resulting from significant impairment of cardiac function. A vast array of biological pathways is now known to be involved in heart failure, including deleterious pathways promoting its development and progression, as well as compensatory cardioprotective pathways. Some of the components of these pathways are now recognized as biomarkers of this condition, and can aid diagnosis, prognostication and guide management. As the understanding of the pathophysiology of heart failure progresses, further candidate biomarkers are being identified. This article reviews the literature regarding the more recently identified biomarkers and outlines areas requiring further study.
Authors:
Jonathan R Dalzell; Colette E Jackson; Theresa A McDonagh; Roy S Gardner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomarkers in medicine     Volume:  3     ISSN:  1752-0371     ISO Abbreviation:  Biomark Med     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-06-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101312535     Medline TA:  Biomark Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  453-63     Citation Subset:  -    
Affiliation:
British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, G12 8TA, UK. j.dalzell@nhs.net
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