Document Detail


A novel aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity.
MedLine Citation:
PMID:  20888232     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Lateral roots are formed at regular intervals along the main root by recurrent specification of founder cells. To date, the mechanism by which branching of the root system is controlled and founder cells become specified remains unknown.
RESULTS: Our study reports the identification of the auxin regulatory components and their target gene, GATA23, which control lateral root founder cell specification. Initially, a meta-analysis of lateral root-related transcriptomic data identified the GATA23 transcription factor. GATA23 is expressed specifically in xylem pole pericycle cells before the first asymmetric division and is correlated with oscillating auxin signaling maxima in the basal meristem. Also, functional studies revealed that GATA23 controls lateral root founder cell identity. Finally, we show that an Aux/IAA28-dependent auxin signaling mechanism in the basal meristem controls GATA23 expression.
CONCLUSIONS: We have identified the first molecular components that control lateral root founder cell identity in the Arabidopsis root. These include an IAA28-dependent auxin signaling module in the basal meristem region that regulates GATA23 expression and thereby lateral root founder cell specification and root branching patterns.
Authors:
Bert De Rybel; Valya Vassileva; Boris Parizot; Marlies Demeulenaere; Wim Grunewald; Dominique Audenaert; Jelle Van Campenhout; Paul Overvoorde; Leentje Jansen; Steffen Vanneste; Barbara Möller; Michael Wilson; Tara Holman; Gert Van Isterdael; Géraldine Brunoud; Marnik Vuylsteke; Teva Vernoux; Lieven De Veylder; Dirk Inzé; Dolf Weijers; Malcolm J Bennett; Tom Beeckman
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-09-30
Journal Detail:
Title:  Current biology : CB     Volume:  20     ISSN:  1879-0445     ISO Abbreviation:  Curr. Biol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-12     Completed Date:  2011-01-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1697-706     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Plant Systems Biology, VIB, Technologiepark 927, B-9052 Ghent, Belgium.
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MeSH Terms
Descriptor/Qualifier:
GATA Transcription Factors / genetics,  metabolism*
Gene Expression Regulation, Plant
Indoleacetic Acids / metabolism*
Molecular Sequence Data
Plant Proteins / genetics,  metabolism*
Plant Roots / cytology,  growth & development*
Plants* / anatomy & histology,  genetics,  growth & development
Signal Transduction*
Two-Hybrid System Techniques
Grant Support
ID/Acronym/Agency:
//Biotechnology and Biological Sciences Research Council
Chemical
Reg. No./Substance:
0/GATA Transcription Factors; 0/Indoleacetic Acids; 0/Plant Proteins
Comments/Corrections
Comment In:
Curr Biol. 2010 Oct 12;20(19):R843-5   [PMID:  20937469 ]

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