| Novel Multimodality Imaging and Physiologic Assessments Clarify Choke-Point Physiology and Airway Wall Structure in Expiratory Central Airway Collapse. | |
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MedLine Citation:
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PMID: 22005343 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Choke points and airway wall structure in expiratory central airway collapse are poorly defined. Computed tomography (CT), white light bronchoscopy (WLB), endobronchial ultrasound (EBUS), vibration response imaging (VRI), spirometry, impulse oscillometry (IOS), negative expiratory pressure (NEP), and intraluminal catheter airway pressure measurements (ICAPM), were used in a patient with cough, dyspnea and recurrent pulmonary infections. CT and WLB identified dynamic collapse of the trachea and mainstem bronchi consistent with severe crescent tracheobronchomalacia. Spirometry showed severe obstruction. EBUS revealed collapse of the airway cartilage and VRI, fluttering at both lung zones. IOS and NEP suggested the tidal expiratory flow limitation in the intrathoracic airways. ICAPM identified the choke point in the lower trachea. After Y-stent insertion, the choke point migrated distally. Imaging studies revealed improved airway dynamics, airway patency, and ventilatory function. Novel imaging and physiologic assessments could be used to localize choke points and airway wall structure in tracheobronchomalacia. |
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Authors:
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Hiroshi Handa; Teruomi Miyazawa; Septimiu D Murgu; Hiroki Nishine; Noriaki Kurimoto; Jyongsu Haung; Henri G Colt |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-13 |
Journal Detail:
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Title: Respiratory care Volume: - ISSN: 0020-1324 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7510357 Medline TA: Respir Care Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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