Document Detail


Novel Approaches for Preventing or Limiting Events in Diabetic Patients (Naples-Diabetes) Trial: A Randomized Comparison of 3 Drug-Eluting Stents in Diabetic Patients.
MedLine Citation:
PMID:  21364149     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background-To expand the paucity of data on the efficacy of various drug-eluting stents in diabetic patients. METHODS AND RESULTS: =0.006 by log-rank test). The post hoc comparisons showed no significant difference between Cypher versus Taxus groups (adjusted P=1.0) but a higher MACE rate in the Endeavor group versus both the Cypher group (adjusted P=0.012) and the Taxus group (adjusted P=0.075). Independent predictors of 3-year MACE at Cox analysis were treatment by Endeavor versus Cypher stent (2.35 [95% confidence interval, 1.07 to 5.41]; P=0.030), multivessel disease (hazard ratio, 1.78 [95% confidence interval, 1.06 to 2.66]; P=0.031), diabetic retinopathy (hazard ratio, 1.60; [95% confidence interval, 1.03 to 2.76]; P=0.038), and poor metabolic control (hazard ratio, 1.60; [95% confidence interval, 1.02 to 2.52]; P=0.048). Conclusions-The present pilot study suggests that in diabetic patients, the Endeavor stent is associated with a higher 3-year MACE rate when compared with Cypher and Taxus stents.
Authors:
Carlo Briguori; Flavio Airoldi; Gabriella Visconti; Amelia Focaccio; Gianluca Caiazzo; Bruno Golia; Giuseppe Biondi-Zoccai; Bruno Ricciardelli; Gerolama Condorelli
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-1
Journal Detail:
Title:  Circulation. Cardiovascular interventions     Volume:  -     ISSN:  1941-7632     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101499602     Medline TA:  Circ Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Laboratory of Interventional Cardiology and Department of Cardiology, Clinica Mediterranea, Naples, Italy; Laboratory of Interventional Cardiology IRCCS Multimedica, Milan, Italy; the Division of Cardiology, University of Modena e Reggio Emilia, Modena, Italy; and Dipartimento di Biologia e Patologia Cellulare e Molecolare, "Federico II" University, Naples, Italy.
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