Document Detail


Novel ABA- and dehydration-inducible aldehyde dehydrogenase genes isolated from the resurrection plant Craterostigma plantagineum and Arabidopsis thaliana.
MedLine Citation:
PMID:  11849595     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to identify genes that are critical for the ABA-dependent stress response in the resurrection plant Craterostigma plantagineum, a gene was isolated with homology to class 3 variable substrate aldehyde dehydrogenases (ALDH). The C. plantagineum gene Cp-ALDH constitutes a novel class of plant ALDHs. In a search for corresponding genes from Arabidopsis thaliana, Ath-ALDH3 and Ath-ALDH4 were isolated, showing 70% and 80% similarity to Cp-ALDH. Phylogenetically, the Cp- and Ath-ALDH3 and -ALDH4 proteins are closely related to aldehyde dehydrogenases from bacteria and mammalian species and are separated from known plant ALDHs and betaine-aldehyde dehydrogenases (BADH). Cp-ALDH transcript and polypeptide are up-regulated in vegetative tissues and callus in response to dehydration or ABA-treatment. Ath-ALDH3 expression was induced in response to dehydration and ABA treatment, while Ath-ALDH4 is constitutively expressed at a low level. Recombinant Cp-ALDH protein oxidizes nonanal, propionaldehyde and acetaldehyde, with Km values of 2.2 microm, 0.27 mm and 3.23 mm, respectively, in an NAD-dependent manner. Immunogold electron microscopy shows that Cp-ALDH is localized in plastids.
Authors:
H H Kirch; A Nair; D Bartels
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Plant journal : for cell and molecular biology     Volume:  28     ISSN:  0960-7412     ISO Abbreviation:  Plant J.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2002-02-18     Completed Date:  2002-03-19     Revised Date:  2006-11-07    
Medline Journal Info:
Nlm Unique ID:  9207397     Medline TA:  Plant J     Country:  England    
Other Details:
Languages:  eng     Pagination:  555-67     Citation Subset:  IM    
Affiliation:
Institute of Botany, University of Bonn, Kirschallee 1, 53115 Bonn, Germany. hhkirch@uni-bonn.de
Data Bank Information
Bank Name/Acc. No.:
GENBANK/AJ306960;  AJ306961
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MeSH Terms
Descriptor/Qualifier:
Abscisic Acid / metabolism*
Aldehyde Dehydrogenase / chemistry,  genetics*
Amino Acid Sequence
Angiosperms / enzymology,  genetics*
Arabidopsis / enzymology,  genetics*
Base Sequence
DNA Primers
Escherichia coli / genetics
Molecular Sequence Data
Sequence Homology, Amino Acid
Water / metabolism*
Chemical
Reg. No./Substance:
0/DNA Primers; 21293-29-8/Abscisic Acid; 7732-18-5/Water; EC 1.2.1.3/Aldehyde Dehydrogenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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