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Notoamide E: Biosynthetic incorporation into notoamides C and D in cultures of Aspergillus versicolor NRRL 35600.
MedLine Citation:
PMID:  22140279     Owner:  NLM     Status:  Publisher    
Notoamide E, a short-lived secondary metabolite, has been proposed as a biosynthetic intermediate to several advanced metabolites isolated from Aspergillus versicolor. In order to verify the role of this indole alkaloid along the biosynthetic pathway, synthetic doubly (13)C-labeled notoamide E was fed to Aspergillus versicolor. Analysis of the metabolites showed significant incorporation of notoamide E into the natural products notoamides C and D.
Jennifer M Finefield; Thomas J Greshock; David H Sherman; Sachiko Tsukamoto; Robert M Williams
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Publication Detail:
Journal Detail:
Title:  Tetrahedron letters     Volume:  52     ISSN:  0040-4039     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-12-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984819R     Medline TA:  Tetrahedron Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1987-1989     Citation Subset:  -    
Department of Chemistry, Colorado State University, 1301 Center Avenue, Fort Collins, Colorado 80523, U.S.A.
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Grant Support
R01 CA070375-10//NCI NIH HHS; R01 CA070375-11//NCI NIH HHS; R01 CA070375-12//NCI NIH HHS; R01 CA070375-13//NCI NIH HHS; R01 CA070375-14//NCI NIH HHS; R01 CA070375-15//NCI NIH HHS; R01 CA070375-16//NCI NIH HHS

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