Document Detail

Not all pustules are infective in nature: acute generalised exanthematous pustulosis causing pustular eruptions in an elderly woman.
MedLine Citation:
PMID:  15968449     Owner:  NLM     Status:  MEDLINE    
Acute generalised exanthematous pustulosis (AGEP) is an adverse drug reaction that can occur in any age group. It is commonly mistaken as pustular psoriasis or cutaneous infection, resulting in unnecessary commencement of medications such as methotrexate and antibiotics that can cause harm to the patient or interact and adversely affect the efficacy of other medications. Early diagnosis of AGEP avoids unnecessary investigations and treatment, which not only can harm the patient but also escalate health care, as the condition is self-limiting. This case report illustrates AGEP secondary to Cefaclor occurring in a 72-year-old Chinese woman. Although the literature has documented the occurrence of AGEP with Cefaclor, the unique feature of this case is the occurrence of AGEP following repeated uneventful courses of Cefaclor. This case highlights that AGEP must never be forgotten in the work-up for pustular eruptions in an elderly patient.
Y C Kwah; Y H Leow
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  46     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-06-21     Completed Date:  2005-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  349-51     Citation Subset:  IM    
National Skin Centre, 1 Mandalay Road, Singapore 308205.
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MeSH Terms
Acute Disease
Anti-Bacterial Agents / adverse effects*
Cefaclor / adverse effects*
Drug Eruptions / diagnosis,  etiology*
Reg. No./Substance:
0/Anti-Bacterial Agents; 53994-73-3/Cefaclor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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