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Nosocomial transmission of Community-acquired Methicillin-Resistant Staphylococcus aureus in a Well-Infant Nursery of a Teaching Hospital.
MedLine Citation:
PMID:  22640461     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background:  Infection due to community-acquired strains of methicillin-resistant Staphylococcus aureus (CA-MRSA) has been reported with increasing frequency. We describe a nosocomial transmission of CA-MRSA involving 13 neonates and 2 mothers in a well-infant nursery in a teaching hospital in Saudi. Methods:  From October to November 2009, temporally related cases of CA-MRSA skin and soft tissue infection occurred in newborns shortly after discharge from a well infant nursery. An outbreak investigation including case identification, review of medical records, staff screening, environmental cultures, pulsed-field gel electrophoresis, and a case-control study were conducted. Controls were selected from among asymptomatic neonates admitted to the same nursery and matched for the day of admission. Results:  Fifteen cases were found to be CA-MRSA-positive: 13 neonates and two mothers. The crude attack rate among neonates was 5.5% during the outbreak period. All 13 neonates presented with skin and soft-tissue infection; one of the mothers had mastitis and a breast abscess.The source of the outbreak was not evident. Pulsed-field gel electrophoresis showed that all of the tested isolates from one strain except one, all contained the staphylococcal cassette chromosome mec (SCCmec) type IV. Conclusion:  MRSA strains that initially emerged in the community are now causing disease in healthcare settings. Adherence to standard infection control practices, including consistent hand hygiene, in newborn nurseries is important to prevent transmission in such settings. © 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.
Authors:
Sarah Alsubaie; Khawater Bahkali; Ali M Somily; Fahad Alzamil; Abdulkareem Alrabiaah; Abdulkareem Alaska; Fatmah Alkhattaf; Abdelmageed Kambal; Ahmed A Al-Qahtani; Mohammed N Al-Ahdal
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-28
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  -     ISSN:  1442-200X     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.
Affiliation:
Department of Pediatrics, College of Medicine, King Saud University and King Khalid University Hospital, Riyadh, Saudi Arabia Department of Infection Prevention and Control, College of Medicine, King Saud University and King Khalid University Hospital, Riyadh, Saudi Arabia Department of Pathology, Microbiology Unit, College of Medicine, King Saud University and King Khalid University Hospital, Riyadh, Saudi Arabia Department of Medicine, College of Medicine, King Saud University and King Khalid University Hospital, Riyadh, Saudi Arabia Department of Pathology and Laboratory Medicine, Molecular Virology and Infectious Diseases Section, Research Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
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