Document Detail

Nosocomial outbreak of colonization and infection with Stenotrophomonas maltophilia in preterm infants associated with contaminated tap water.
MedLine Citation:
PMID:  9692603     Owner:  NLM     Status:  MEDLINE    
Between March and May 1996 Stenotrophomonas maltophilia was cultured from endotracheal aspirate samples from five preterm infants in a neonatal intensive care unit (NICU). Four infants were superficially colonized, but a fifth died due to S. maltophilia septicaemia. S. maltophilia was cultured from tap water from three outlets in the NICU including one with a previously unnoticed defective sink drain. Water from these outlets was used to wash the preterm infants. Environmental and clinical S. maltophilia isolates yielded identical banding patterns on random arbitrary polymorphic DNA (RAPD) PCR analysis. The outbreak was controlled by reinforcement of hand disinfection, limitation of the use of tap water for hand washing and by using sterile water to wash the preterm infants. We conclude that tap water should not be used for washing preterm infants in the NICU, unless steps are taken to prevent microbial growth in the outlets.
P E Verweij; J F Meis; V Christmann; M Van der Bor; W J Melchers; B G Hilderink; A Voss
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Epidemiology and infection     Volume:  120     ISSN:  0950-2688     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-08-13     Completed Date:  1998-08-13     Revised Date:  2010-03-03    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  251-6     Citation Subset:  IM    
Department of Medical Microbiology, University Hospital Nijmegen, The Netherlands.
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MeSH Terms
Cross Infection / epidemiology*
Disease Outbreaks*
Gram-Negative Bacterial Infections / epidemiology*
Infant, Newborn
Infant, Premature
Water Microbiology*
Water Supply*

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