Document Detail

Nosocomial meningitis caused by Enterobacteriaceae: risk factors and outcome in 18 cases in 1992-2007.
MedLine Citation:
PMID:  17558373     Owner:  NLM     Status:  MEDLINE    
Nosocomial neuroinfections due to Enterobacteriaceae represented 9.5% in our cohort of 171 cases of paediatric meningitis within last 15 years. Commonest etiologic agents was E. coli - 9 (50%) followed by Klebsiella pneumoniae - 3 (16,7%) and Enterobacter cloacae. Citrobacter freundii, Proteus mirabilis and Salmonella enteritidis (1 each). Commonest risk factors were neonatal age 13 - (72.2%), very low birth weight 5 (27.8%), craniocerebral trauma - 4 (22.2%) and neurosurgery - 5 (27.8%). All but 1 case were treated with antibiotics: 8 with III-rd and 3 with IV-th generation cephalosporins (ceftazidim, cefotaxim and cefepim) 2 with meropenem and 4 with ciprofloxacin: Nosocomial meningitis due to enterobacteriaceae was associated with significantly high mortality (29.9% vs. 15.1% in all cohort of pediatric meningitis - p<0.02).
J Benca; A Ondrusova; B Rudinsky; F Bauer; M Kovac
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuro endocrinology letters     Volume:  28 Suppl 2     ISSN:  0172-780X     ISO Abbreviation:  Neuro Endocrinol. Lett.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-12-18     Completed Date:  2008-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008373     Medline TA:  Neuro Endocrinol Lett     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  27-9     Citation Subset:  IM    
John Paul School of Missiology and Tropical Health, St. Elisabeth University College, Bratislava, Slovakia.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Child, Preschool
Cross Infection / drug therapy,  etiology,  microbiology*
Drug Resistance, Bacterial
Enterobacteriaceae Infections / complications*,  drug therapy
Infant, Newborn
Meningitis, Bacterial / drug therapy,  etiology,  microbiology*
Risk Factors
Treatment Outcome
Reg. No./Substance:
0/Anti-Bacterial Agents

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