Document Detail


Nosocomial Clostridium difficile reservoir in a neonatal intensive care unit.
MedLine Citation:
PMID:  6494014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new bacteriophage/bacteriocin typing system was used to study Clostridium difficile colonization in a neonatal intensive care unit. C. difficile was isolated from 21 of 62 (34%) stools from 15 of 37 (41%) infants. Colonization was reduced during antimicrobial therapy and for about 1 week thereafter. One of five nurses and one of two parents studied were carriers. Eight isolates were cultured from environmental surfaces. Thirty of 31 C. difficile isolates were found to be a single type, Cld 6,9,10,13; bacteriocin 1320,1537,2304. No C. difficile was found in 29 specimens obtained in the delivery room from mothers and infants, and there was no association of early colonization with vaginal delivery. The data provide strong evidence for nosocomial acquisition of C. difficile by infants in the neonatal intensive care unit. No obvious pathologic role for C. difficile could be identified among colonized infants. Among 22 C. difficile isolates from 7 adult inpatients with diarrhea and 13 healthy infants attending the center's well baby clinic, 4 were the same type as the strain found in the intensive care nursery. Only one of these patients had had direct contact with the neonatal intensive care unit, indicating that the nursery strain may also be found elsewhere in the community.
Authors:
A J Zedd; T L Sell; D R Schaberg; F R Fekety; M S Cooperstock
Related Documents :
12187184 - Cost-effectiveness and choice of infant transport systems.
9305114 - Comparing nursing costs for preterm infants receiving conventional vs. developmental care.
1760064 - A review of newborn medicine in america: european past and guiding ideology.
1562444 - Thermoregulation in low-birth-weight infants.
24108664 - Fetal thrombotic vasculopathy and perinatal thrombosis: should all placentas be examined?
19888444 - Families by adoption and birth: i. mother-infant socio-emotional interactions.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric infectious disease     Volume:  3     ISSN:  0277-9730     ISO Abbreviation:  Pediatr Infect Dis     Publication Date:    1984 Sep-Oct
Date Detail:
Created Date:  1984-12-10     Completed Date:  1984-12-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8209468     Medline TA:  Pediatr Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  429-32     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Carrier State / microbiology*
Clostridium / isolation & purification
Clostridium Infections / diagnosis,  etiology*
Cross Infection / diagnosis,  etiology*
Disease Reservoirs*
Equipment Contamination
Feces / microbiology
Female
Humans
Infant
Infant, Newborn
Intensive Care Units, Neonatal*
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A nosocomial common source outbreak caused by Pseudomonas pickettii.
Next Document:  Criteria for the evaluation of new diagnostic tests.