Document Detail

Nose blowing propels nasal fluid into the paranasal sinuses.
MedLine Citation:
PMID:  10671347     Owner:  NLM     Status:  MEDLINE    
Intranasal pressures were measured in adults during nose blowing, sneezing, and coughing and were used for fluid dynamic modeling. Sinus CT scans were performed after instillation of radiopaque contrast medium into the nasopharynx followed by nose blowing, sneezing, and coughing. The mean (+/-SD) maximal intranasal pressure was 66 (+/-14) mm Hg during 35 nose blows, 4.6 (+/-3.8) mm Hg during 13 sneezes, and 6.6 (+/-3.8) mm Hg during 18 coughing bouts. A single nose blow can propel up to 1 mL of viscous fluid in the middle meatus into the maxillary sinus. Sneezing and coughing do not generate sufficient pressure to propel viscous fluid into the sinus. Contrast medium from the nasopharynx appeared in >/=1 sinuses in 4 of 4 subjects after a nose blow but not after sneezing or coughing.
J M Gwaltney; J O Hendley; C D Phillips; C R Bass; N Mygind; B Winther
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  30     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-04-12     Completed Date:  2000-04-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  387-91     Citation Subset:  IM    
Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA.
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MeSH Terms
Contrast Media
Cough / physiopathology
Models, Biological
Nasal Lavage Fluid*
Nasal Mucosa / secretion*
Nasopharynx / physiology*
Paranasal Sinuses / physiology*,  radiography
Reference Values
Sensitivity and Specificity
Sneezing / physiology
Tomography, X-Ray Computed / methods
Reg. No./Substance:
0/Contrast Media

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