Document Detail


Northern Region Fetal Abnormality Survey results 1987.
MedLine Citation:
PMID:  2139467     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The UK Northern Region Fetal Abnormality Survey was notified of 572 suspected fetal abnormalities in 1987. Of these, 265 (46%) had pediatric surgical implications. Because the registry traces the postnatal outcome of each notification and records congenital abnormalities diagnosed postnatally, it is possible to measure both sensitivity and selectivity of antenatal diagnosis of fetal abnormalities. Cases were divided into five groups: diaphragmatic hernia, abdominal wall defects, intestinal anomalies, neural tube defects, and urological anomalies. Each group comprised cases that were unsuspected, suspected but not confirmed, and suspected and confirmed. Sensitivity was highest in the urological group, but 30% of the notified cases were unconfirmed so selectivity was higher in the abdominal wall and neural tube groups. None of the diaphragmatic hernias and only 14.3% of the intestinal anomalies were correctly suspected. Only 13.5% of all neural tube defects were treated surgically. The Survey has improved cooperation and communication between specialists concerned with the management of fetal abnormalities and this in turn has improved patient care.
Authors:
J E Scott; M Renwick
Related Documents :
20831537 - Hepatotoxicity of alpha-methyldopa in pregnancy.
9196967 - Knowledge about folic acid and the prevention of neural tube defects in two general pra...
79417 - The significance of raised maternal plasma alpha-fetoprotein in twin pregnancy.
6159997 - Concanavalin a reactivity pattern of human amniotic fluid afp examined by crossed affin...
3174917 - The transfer of zinc across the term dually perfused human placental lobule.
7771647 - Ethanol elevates fetal serum glutamate levels in the rat.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  25     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-05-31     Completed Date:  1990-05-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  394-7     Citation Subset:  IM    
Affiliation:
Northern Region Health Authority, Newcastle upon Tyne, England.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abdominal Muscles / abnormalities*
Cohort Studies
Female
Great Britain / epidemiology
Hernia, Diaphragmatic / congenital,  diagnosis*,  epidemiology
Humans
Infant
Infant, Newborn
Intestines / abnormalities*
Male
Neural Tube Defects / diagnosis*,  epidemiology
Prenatal Diagnosis / statistics & numerical data*
Sensitivity and Specificity
Ultrasonography
Urogenital Abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Functional consequences of the genetic polymorphism of the third component of complement.
Next Document:  Effect of enalapril or the thromboxane receptor antagonist, daltroban, in rats with subtotal renal a...