| Normalization of left ventricular function following cardiac resynchronization therapy: left bundle branch block as a potential etiology of dilated cardiomyopathy. | |
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MedLine Citation:
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PMID: 18503236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with chronic heart failure (HF) not infrequently present conduction disturbances, which are most commonly exhibited as a left bundle branch block (LBBB). LBBB is associated with intraventricular conduction delay, paradoxical septal motion, and hemodynamic deterioration, indicating an impairment of left ventricular (LV) function. However, there is controversy as to whether dilated cardiomyopathy leading to HF could develop just as a result of conduction disturbances without apparent pre-existing heart disease. We report here 2 cases of patients with non-ischemic dilated cardiomyopathy and LBBB who had complete reversal of their LV dysfunction and enlargement after cardiac resynchronization therapy, which corrects the LV activation sequence. These cases might support the idea that conduction disturbances themselves can be a principal etiology in the development of dilated cardiomyopathy. |
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Authors:
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Banyo Fujii; Mistuaki Takami |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 72 ISSN: 1346-9843 ISO Abbreviation: Circ. J. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-05-26 Completed Date: 2008-09-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 1030-3 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Saiseikai Shimonoseki General Hospital, 8-5-1 Yasuoka-cho, Shimonoseki 759-6603, Japan. b-fujii@simo.saiseikai.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Bundle-Branch Block / complications*, radionuclide imaging, therapy* Cardiomyopathy, Dilated / etiology*, radionuclide imaging, therapy* Electrocardiography Female Gated Blood-Pool Imaging Heart Catheterization Humans Mitral Valve Insufficiency / ultrasonography Pacemaker, Artificial* Ventricular Function, Left / physiology* |
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