Document Detail

Normal values of volume flow in the internal carotid artery measured by a new angle-independent Doppler technique for evaluating cerebral perfusion.
MedLine Citation:
PMID:  15340809     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Cerebral blood flow is an important parameter when monitoring critically ill patients. Blood flow volume within the internal carotid artery (ICA) was shown to be correlated with the cerebral blood flow. The aim of our study was to provide normal values of the internal carotid artery volume flow using this new technology (QuantixND, Cardiosonix Ltd., Israel). METHOD: The QuantixND System is an angle-independent Doppler system that employs two digital high resolution ultrasound heads within one probe in an defined angle to each other. Thus several flow velocities within the vessel and the vessel diameter can be measured. 77 healthy patients (41 women, 36 men) were included and divided into age groups of ten-year intervals (mean age 48.9 years). Internal carotid artery flow was evaluated as well as physiological and hematological parameters (hematocrit, arterial blood pressure etc). FINDINGS: We found that the blood flow volume in the ICA decreased significantly with age. No side-to-side effects as well as no gender-related differences could be observed. There was no influence of hemoglobin, hematocrit and blood pressure in this healthy population. CONCLUSIONS: There is an age-related decrease in blood flow volume with age that can be easily and exactly determined by the use of the new angle-independent Doppler technique.
K-M Schebesch; S Simka; C Woertgen; A Brawanski; R D Rothoerl
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2004-07-15
Journal Detail:
Title:  Acta neurochirurgica     Volume:  146     ISSN:  0001-6268     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-01     Completed Date:  2004-12-22     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  983-6; discussion 986-7     Citation Subset:  IM    
Department of Neurosurgery, University of Regensburg, Franz-Josef-Strauss Allee 11, 93053 Regensburg, Germany.
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MeSH Terms
Age Factors
Aged, 80 and over
Blood Pressure
Brain / blood supply*
Carotid Artery, Internal / physiology*
Functional Laterality
Middle Aged
Reference Values
Regional Blood Flow
Sensitivity and Specificity
Ultrasonography, Doppler / methods*

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