Document Detail


Normal outcome of pregnancy in chronic myeloid leukemia treated with interferon-alpha in 1st trimester: report of 3 cases and review of the literature.
MedLine Citation:
PMID:  11835347     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three patients with chronic myeloid leukemia (CML) in chronic phase received interferon-alpha during pregnancy, starting from the 1st trimester. No maternal complications were reported. The 3 patients delivered normal looking babies apart from one baby who was found to have transient mild thrombocytopenia. Subsequently these children were followed for 30, 12, and 4 months and all had normal growth and development.
Authors:
A A S Mubarak; I R Kakil; A Awidi; U Al-Homsi; Z Fawzi; M Kelta; A Al-Hassan
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of hematology     Volume:  69     ISSN:  0361-8609     ISO Abbreviation:  Am. J. Hematol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-08     Completed Date:  2002-02-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7610369     Medline TA:  Am J Hematol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  115-8     Citation Subset:  IM    
Copyright Information:
Copyright 2002 Wiley-Liss, Inc.
Affiliation:
Hamad Medical Corporation, Department of Medicine, Hematology/Oncology Division, Doha, Qatar.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Gestational Age*
Humans
Interferon-alpha / adverse effects,  therapeutic use*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy*
Pregnancy
Pregnancy Complications, Neoplastic / drug therapy*
Pregnancy Outcome*
Pregnancy Trimester, First
Chemical
Reg. No./Substance:
0/Interferon-alpha
Comments/Corrections
Comment In:
Am J Hematol. 2006 Feb;81(2):149-50   [PMID:  16432865 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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