Document Detail


'Normal' lung function in rural Australian aborigines.
MedLine Citation:
PMID:  9404585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although lung diseases are a leading cause of premature mortality in Australian Aborigines, little is known about normal lung function in these people. AIM: To develop models for 'normal' spirometric function in rural Australian Aborigines. METHOD: A cross-sectional population-based study of four rural Aboriginal communities was performed in Queensland, Northern Territory and South Australia, Australia. We studied 261 children aged seven-19 years and 332 adults aged 20-80 years who were free of symptoms and had no clinical signs of chronic lung disease. The outcome measures were forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). Multiple linear regression was used to develop models for FEV1 and FVC and comparisons were made with Caucasians and indigenous people from other countries. RESULTS: The Aboriginal people studied had FEV1 and FVC values that were lower (20% and 30% respectively) than those found in Caucasians of the same height, age and gender. As a consequence, they had relatively high FEV1/FVC ratios. Those studied also had forced expiratory volumes that were lower than those found in African Americans and other indigenous peoples. CONCLUSIONS: Apparently healthy rural Aboriginal people have low forced expiratory volumes when contrasted with Caucasians and indigenous peoples such as African Americans. More research is required to determine if this is 'normal' or a product of the suboptimal environment into which many Aboriginal people are born.
Authors:
A J Veale; J K Peat; C M Salome; A J Woolcock; J E Thompson
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Australian and New Zealand journal of medicine     Volume:  27     ISSN:  0004-8291     ISO Abbreviation:  Aust N Z J Med     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1998-01-22     Completed Date:  1998-01-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1264322     Medline TA:  Aust N Z J Med     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  543-9     Citation Subset:  IM    
Affiliation:
National Centre for Epidemiology and Population Health, Canberra.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Cross-Sectional Studies
European Continental Ancestry Group
Female
Forced Expiratory Volume
Humans
Linear Models
Male
Middle Aged
Northern Territory
Oceanic Ancestry Group*
Queensland
Reference Values
Respiratory Mechanics / physiology*
Rural Population
Smoking / adverse effects
South Australia
Spirometry
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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