| Normal intelligence in female and male patients with congenital adrenal hyperplasia. | |
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MedLine Citation:
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PMID: 20976263 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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We provide evidence regarding the nature, causes, and consequences of intelligence in patients with 21-hydroxylase deficient congenital adrenal hyperplasia (CAH). Intelligence and quality of life (psychological adjustment) were measured on multiple occasions from childhood to young adulthood in 104 patients with CAH (62 females, 42 males) and 88 unaffected relatives (31 females, 57 males). Information on disease severity (CAH type, age at diagnosis, genital virilization for girls) and salt-wasting crises was obtained from medical records. There was no evidence of intellectual deficit in either female or male patients with CAH. Intelligence was not significantly associated with psychological adjustment or disease characteristics. CAH itself does not appear to increase risk for poor intellectual function. In a sample of patients with generally good disease control, intelligence is not related to adjustment problems, disease severity, or salt-wasting crises. |
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Authors:
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Sheri A Berenbaum; Kristina Korman Bryk; Stephen C Duck |
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Publication Detail:
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Type: Journal Article Date: 2010-10-07 |
Journal Detail:
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Title: International journal of pediatric endocrinology Volume: 2010 ISSN: 1687-9856 ISO Abbreviation: Int J Pediatr Endocrinol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-10-26 Completed Date: 2011-07-14 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 101516111 Medline TA: Int J Pediatr Endocrinol Country: Egypt |
Other Details:
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Languages: eng Pagination: 853103 Citation Subset: - |
Affiliation:
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Departments of Psychology and Pediatrics, The Pennsylvania State University, University Park, PA 16803, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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