Document Detail

Normal human bronchial immunoglobulins and proteins: effects of cigarette smoking.
MedLine Citation:
PMID:  879597     Owner:  NLM     Status:  MEDLINE    
Selected proteins were compared in bronchial lavage fluids recovered from 36 healthy nonsmokers and 19 healthy cigarette smokers. Although fluids lavaged from smokers contained 4 times as many cells (more than 80 per cent macrophages) as fluids from nonsmokers, there were no quantitative differences between the two groups in immunoglobulin A, a1-antitrypsin, a2-globulin, transferrin, or albumin content. However, immunoglobulin G content of bronchial fluids from smokers was twice as high as that from nonsmokers. This selective increase in immunoglobulin is compatible either with stimulated local bronchial immunoglobulin production or the selective exudation of plasma immunoglobulin into alveolar spaces in response to inhaled cigarette smoke.
G A Warr; R R Martin; P M Sharp; R D Rossen
Related Documents :
16465837 - Unchanged prevalence of shell disease in the edible crab cancer pagurus four years afte...
16988927 - Influence of glyphosate on rhizoctonia and fusarium root rot in sugar beet.
7904667 - Coeliac disease in the year 2000: exploring the iceberg.
12608567 - Bacteraemia in free-ranging hawaiian green turtles chelonia mydas with fibropapillomato...
18690497 - Neurophysiological markers.
1543667 - Nonneoplastic hematologic disease.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American review of respiratory disease     Volume:  116     ISSN:  0003-0805     ISO Abbreviation:  Am. Rev. Respir. Dis.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-08-25     Completed Date:  1977-08-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370523     Medline TA:  Am Rev Respir Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  25-30     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Body Fluids / analysis*,  cytology
Bronchi / secretion*
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Immunoglobulins / analysis*
Proteins / analysis*
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulins; 0/Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The influence of cigarette smoking and sex on theophylline disposition.
Next Document:  Pulmonary impairment from chronic exposure to sulfur dioxide in a smelter.