Document Detail

Normal hemodynamic, ventilatory, and metabolic response to exercise.
MedLine Citation:
PMID:  6639238     Owner:  NLM     Status:  MEDLINE    
An integrated response to exercise must occur among the cardiovascular, pulmonary, and regional circulations. The increased oxygen inspired by the lungs must be transported through the circulation and taken up by the exercising muscles. The cardiovascular adaptations to maximal exercise include an increase in cardiac output (predominantly by a rise in the heart rate) and a widening of the arteriovenous oxygen difference. In the regional circulations, there are increases in both the rate of skeletal blood flow and the rate of arteriovenous oxygen extraction. Pulmonary ventilation also increases by a rise in both the respiratory rate and tidal volume. The fuel necessary for maximal exercise is derived initially from accelerated breakdown of muscle glycogen and later by an increase in the hepatic glucose production. A combination of aerobic and anaerobic metabolism generates the adenosine triphosphate necessary for muscular contraction.
D A Weiner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  143     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2173-5     Citation Subset:  AIM; IM; S    
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MeSH Terms
Blood Circulation
Cardiovascular Physiological Phenomena*
Energy Metabolism
Physical Exertion*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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