Document Detail

Normal cardiac contractility in patients with congenital nemaline myopathy.
MedLine Citation:
PMID:  3221984     Owner:  NLM     Status:  MEDLINE    
We made cardiac investigations in 12 patients aged 5-25 years with congenital nemaline myopathy by physical examination, electrocardiography, chest-X-ray and echocardiography to find out whether they showed signs of structural anomalies, specific heart muscle disease, conduction defects or cor pulmonale. One patient had a small ventricular septal defect and one had mitral valve prolapse, neither of which had caused haemodynamic alterations. In the other patients, cardiac findings were normal. Cardiac follow-up seems indicated, however, since cor pulmonale may develop in these patients because of their small vital capacity and restricted breathing movements.
A L Airenne; C Wallgren-Pettersson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuropediatrics     Volume:  19     ISSN:  0174-304X     ISO Abbreviation:  Neuropediatrics     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1989-03-22     Completed Date:  1989-03-22     Revised Date:  2008-01-16    
Medline Journal Info:
Nlm Unique ID:  8101187     Medline TA:  Neuropediatrics     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  115-7     Citation Subset:  IM    
Jorvi Hospital, Espoo, Finland.
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MeSH Terms
Cardiomyopathies / congenital,  physiopathology*
Child, Preschool
Heart / physiopathology*
Heart Defects, Congenital / physiopathology*
Myocardial Contraction*

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