Document Detail

Normal hemoglobin at the age of 1 year does not protect infants from developing iron deficiency anemia in the second year of life.
MedLine Citation:
PMID:  21792044     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Iron deficiency anemia (IDA) is the most common hematologic disorder worldwide. Measures to prevent IDA in infants have been successful with questionable sustainability.
AIM: To evaluate the incidence of developing IDA in the second year of life, in infants who were nonanemic at the age of 1 year on routine blood test.
METHODS: Blood samples were obtained from 193, 24-month-old toddlers, from 2 large clinics of both main sectors in Southern Israel, comparable for lower economic status. IDA was defined as hemoglobin < 11 gr% and microcytosis as mean corpuscular volume < 70 fL.
RESULTS: IDA was detected in 8 of 118 Bedouins (5 males) and in 10 of 75 Jewish (6 males) infants (P < 0.01). The probability of a nonanemic child to develop IDA in the second year of life for the whole study population was 9.3% (18 of 193 infants) and significantly higher in the Jewish population (13.3.0% vs. 6.8%, P < 0.01).
CONCLUSIONS: Given the difficulty of toddlers to maintain a non-IDA status, and the very low probability of iron overload, our results clearly support the need to continue iron supplementation into the second year.
Asher M Moser; Jacob Urkin; Hanna Shalev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  33     ISSN:  1536-3678     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-27     Completed Date:  2011-09-27     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  467-9     Citation Subset:  IM    
Department of Pediatric Hematology/Oncology, Soroka Medical Center, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
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MeSH Terms
Anemia, Iron-Deficiency / epidemiology*,  prevention & control*
Child, Preschool
Hemoglobins / analysis
Iron / administration & dosage*,  blood,  deficiency*
Israel / epidemiology
Time Factors
Reg. No./Substance:
0/Hemoglobins; 7439-89-6/Iron

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