| Norepinephrine and gamma-aminobutyric acid in amyotrophic lateral sclerosis. | |
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MedLine Citation:
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PMID: 7188643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with amyotrophic lateral sclerosis have increased levels of the neutrotransmitter norepinephrine in blood and cerebrospinal fluid and depressed levels of the inhibitory neurotransmitter gamma-aminobutyric acid in cerebrospinal fluid. These neurochemical alterations are most marked in patients bedridden with advanced disease, appear interrelated, and lead to cardiovascular alterations in patients with amyotrophic lateral sclerosis. |
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Authors:
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M G Ziegler; B R Brooks; C R Lake; J H Wood; S J Enna |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Neurology Volume: 30 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 1980 Jan |
Date Detail:
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Created Date: 1980-02-28 Completed Date: 1980-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 98-101 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amyotrophic Lateral Sclerosis / blood, cerebrospinal fluid* Female Humans Male Muscular Diseases / blood, cerebrospinal fluid Nervous System Diseases / blood, cerebrospinal fluid Norepinephrine / blood, cerebrospinal fluid* gamma-Aminobutyric Acid / blood, cerebrospinal fluid* |
| Chemical | |
Reg. No./Substance:
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51-41-2/Norepinephrine; 56-12-2/gamma-Aminobutyric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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