| Nonthermal effects of mobile-phone frequency microwaves on uteroplacental functions in pregnant rats. | |
| | |
MedLine Citation:
|
PMID: 12759101 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Exposure to high-density microwaves can cause detrimental effects on the testis, eye, and other tissues, and induce significant biologic changes through thermal actions. To examine nonthermal effect of continuous wave (CW) 915MHz microwaves used in cellular phones, we compared the effects of microwaves with those of heat. Thirty-six pregnant rats were assigned to six groups: rats exposed to microwaves at 0.6 or 3mW/cm(2) incident power density at 915MHz for 90min, rats immersed in water at 38 or 40 degrees C, which induces about the same increase in colonic temperature of 1.0 or 3.5 degrees C as 0.6 or 3mW/cm(2) microwaves, respectively; rats immersed in water at 34 degrees C, which is considered to be thermoneutral; and control rats. We identified significant differences in the uteroplacental circulation, and in placental endocrine and immune functions between pregnant rats immersed in water at 34 and 38 degrees C, but not between rats immersed at 38 degrees C and those exposed to microwaves at 0.6mW/cm(2). By contrast, we observed significant decreases in uteroplacental blood flow and estradiol in rats exposed to microwaves at 3mW/cm(2) as compared with those immersed in water at 40 degrees C. These results suggest microwaves at 0.6mW/cm(2) at 915MHz, equal to a specific absorption rate (SAR) of 0.4W/kg, which is the maximum permissible exposure level recommended by the American National Standards Institute (ANSI), do not exert nonthermal effects on blood estradiol and progesterone, on splenic natural killer cell activity, on the uteroplacental circulation. |
| | |
Authors:
|
Hiroyuki Nakamura; Ichiyo Matsuzaki; Kotaro Hatta; Yoshitaka Nobukuni; Yasuhiro Kambayashi; Keiki Ogino |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Reproductive toxicology (Elmsford, N.Y.) Volume: 17 ISSN: 0890-6238 ISO Abbreviation: Reprod. Toxicol. Publication Date: 2003 May-Jun |
Date Detail:
|
Created Date: 2003-05-21 Completed Date: 2004-02-06 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8803591 Medline TA: Reprod Toxicol Country: United States |
Other Details:
|
Languages: eng Pagination: 321-6 Citation Subset: IM |
Affiliation:
|
Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, 920-8640, Japan. hiro-n@po.incl.ne.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cellular Phone* Cytotoxicity, Immunologic / radiation effects Estradiol / blood Female Immersion / adverse effects Killer Cells, Natural / immunology, radiation effects Microwaves / adverse effects* Placental Circulation / immunology, physiology, radiation effects* Pregnancy Progesterone / blood Rats Rats, Wistar Spleen / cytology, immunology, radiation effects Temperature |
| Chemical | |
Reg. No./Substance:
|
50-28-2/Estradiol; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Novel Calbindin-D(9k) protein as a useful biomarker for environmental estrogenic compounds in the ut...
Next Document: Two-generation reproductive study in mink fed diisopropyl methylphosphonate (DIMP).