| Nonsteroidal anti-inflammatory drug colopathy mimicking malignant masses of the colon: a report of three cases and review of the literature. | |
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MedLine Citation:
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PMID: 21140699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The adverse effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on the colon have been reported as a wide spectrum of symptoms, signs, and endoscopic findings. Despite the extensive use of NSAIDs, and the potential seriousness of NSAID colopathy, this condition often goes unrecognized or misdiagnosed. We report three cases of NSAID colopathy in which the diagnosis of malignancy was incorrectly made based on endoscopic findings. Before any surgical intervention, we entertained the diagnosis of NSAID colopathy based on clinical presentation. Ultimately, in two of the three cases, surgery was avoided and the lesions resolved. We present their clinical course and a review of the pertinent literature reviewing theories of the pathophysiology, the range of clinical presentations, and the pathological findings of this entity. |
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Authors:
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David M Margolius; Thomas E Cataldo |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The American surgeon Volume: 76 ISSN: 0003-1348 ISO Abbreviation: Am Surg Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-12-09 Completed Date: 2011-01-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370522 Medline TA: Am Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1282-6 Citation Subset: IM |
Affiliation:
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Warren Alpert Medical School of Brown University, Brown University, Providence, Rhode Island 02905, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anti-Inflammatory Agents, Non-Steroidal / adverse effects* Colitis / chemically induced*, diagnosis, physiopathology, surgery Colonic Neoplasms / diagnosis Colonoscopy Diagnosis, Differential Female Gastrointestinal Hemorrhage / chemically induced, diagnosis, physiopathology, surgery Humans Male Middle Aged Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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