| Nonspecific reactions with the intradermal test for hydatidosis in persons with other helminth infections. | |
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MedLine Citation:
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PMID: 53018 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A partially purified Echinococcus antigen solution, prepared by boiling hydatid cyst fluid, was used in the intradermal test for hydatid disease in a Peruvian population. An unexpectedly high rate of positive reactions and poor agreement with serological tests suggested the presence of some agent(s) which produced cross-reactions with Echinococcus granulosus antigens in the intradermal test. Testing of hospital patients infected with a variety of helminths demonstrated nonspecific reactions in persons with Hymenolepis nana, Taenia spp., and Fasciola hepatica infections, mixed parasitisms, and several non-helminth pathological conditions. The findings contraindicated the use of the intradermal test for epidemiological surveys of hydatid disease. It is pointed out that intradermal test positivity rates cannot be used as synonymous with infection prevalence and regional differences do not necessarily reflect differences in the prevalence of E. granulosus infection. The greater specificity of some serological tests favor their use for epidemiological purposes. |
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Authors:
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P M Schantz; R E Ortiz-Valqui; H Lumbreras |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 24 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1975 Sep |
Date Detail:
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Created Date: 1976-01-16 Completed Date: 1976-01-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 849-52 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Heterophile
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isolation & purification Echinococcosis / immunology* Echinococcus / isolation & purification Epitopes Female Helminthiasis / immunology Humans Intradermal Tests* Peru Skin Tests* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Heterophile; 0/Epitopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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