Document Detail

Nonspecific aerobic vaginitis and pregnancy.
MedLine Citation:
PMID:  11316936     Owner:  NLM     Status:  MEDLINE    
During the period 1996-1998, cervical swabs of 50 pregnant women with subacute amniotic infection syndrome (AIS) and the semen of their consorts were bacteriologically analyzed. In the control group were 50 healthy pregnant women and their consorts too. Pathogenic bacteria (the most common were Escherichia coli, Staphylococcus haemolyticus, Chlamydia trachomatis and Ureaplasma urealyticum) were isolated from the cervical swab of 50 pregnant patients with AIS in 86.0% of them, while in the control group of healthy pregnant women in 28.0%. Pathogenic bacteria were present in 70.0% of semen of consorts pregnant women with AIS and only in 30.0% of semen of the control group. The congruity of pathogenic bacteria in the cervical swab and semen in the investigated group was 69.2%, while only 35.7% in the control group. Following erythromycin, cefuroxime and local tetracyclin treatment, the negativization of the cervical swab resulted in 30 pregnant patients with AIS, while the colonization persisted in 20 of them. The outcome of pregnancy was significantly better in cases with negativization of the cervical swab: perinatal loss was 6.7%, while in cases with persistent infection it was 55.0%. The authors presume the amniotic infection syndrome should be ascending manifestation of nonspecific vaginitis, which is maintained by the consort's urogenital infection. AIS should be classified as a 'sexually-transmitted disease'.
D Curzik; A Drazancić; Z Hrgović
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  16     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2001 May-Jun
Date Detail:
Created Date:  2001-04-24     Completed Date:  2001-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  187-92     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Department of Obstetrics and Gynecology, Clinical Hospital, Osijek, Croatia.
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MeSH Terms
Bacteria, Aerobic / isolation & purification
Cervix Uteri / microbiology
Pregnancy Complications, Infectious / diagnosis*,  epidemiology
Pregnancy Outcome / epidemiology*
Semen / microbiology
Sexually Transmitted Diseases, Bacterial / diagnosis,  epidemiology
Vaginosis, Bacterial / diagnosis*,  epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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