Document Detail

Nonseptic cerebral emboli of cardiac origin.
MedLine Citation:
PMID:  6486983     Owner:  NLM     Status:  MEDLINE    
There is considerable debate regarding immediate anticoagulation with heparin sodium for patients suspected of having acute cerebral embolism from a cardiac source. We studied 60 consecutive hospitalized patients suspected of having a nonseptic cardiogenic cerebral embolism who, with one exception, were treated with immediate full-dose anticoagulation. None of the patients had progression of their neurologic deficits secondary to intracranial hemorrhage or recurrent embolism, and there were no deaths secondary to anticoagulant therapy. One patient had punctate hemorrhages in the area of infarction, but remained clinically stable. In light of our experience and a review of the literature, we conclude that immediate anticoagulation is judiciously safe in selected patients after nonseptic embolic stroke of cardiac origin, provided early cranial computed tomography fails to demonstrate hemorrhagic infarction.
G J Martin; J Biller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  144     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-11-01     Completed Date:  1984-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1997-9     Citation Subset:  AIM; IM    
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MeSH Terms
Atrial Fibrillation / complications
Cerebral Hemorrhage / etiology
Coronary Disease / complications
Heart Diseases / complications*
Heart Valve Diseases / complications
Heparin / therapeutic use
Intracranial Embolism and Thrombosis / drug therapy,  etiology*,  radiography
Middle Aged
Tomography, X-Ray Computed
Reg. No./Substance:

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