Document Detail

Nonreassuring fetal heart rate patterns and nucleated red blood cells in term neonates.
MedLine Citation:
PMID:  20499074     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: The aim of this study was to evaluate the association between nonreassuring fetal heart rate patterns during labor and umbilical cord nucleated red blood cell counts.
METHODS: Nucleated red blood cell data was collected prospectively from 41 singleton term neonates presented with nonreassuring fetal heart rate patterns and/or meconium stained amniotic fluid during labor (study group) and from 45 term neonates without any evidence of nonreassuring fetal status (controls). Umbilical artery pH, blood gases and base excess were also determined to investigate the correlation between independent variables.
RESULTS: The median nucleated red blood cells per 100 white blood cells were 13 (range 0-37) in the study group and 8 (range 0-21) in the control group. Stepwise regression analysis have identified meconium stained amniotic fluid (R (2) = 0.15, p < 0.0001) and umbilical artery PO(2) (R (2) = 0.1, p = 0.002) as independent variables associated with elevated NRBC counts in patients with nonreassuring fetal heart rate patterns.
CONCLUSIONS: Nucleated red blood cells in the cord blood of newborns were found to be elevated in patients with nonreassuring FHR patterns during labor. However, the wide range and the poor correlation of NRBC count with umbilical artery pH and blood gas values limit its clinical utility as a marker for fetal hypoxia.
E Ebru Kovalak; F Suat Dede; Orhan Gelisen; Hulya Dede; Ali Haberal
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Publication Detail:
Type:  Journal Article     Date:  2010-05-25
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  283     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1005-9     Citation Subset:  IM    
Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey.
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