Document Detail


Nonpulsatile cerebral perfusion in Takayasu's arteritis.
MedLine Citation:
PMID:  12722503     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A nonpulsatile cerebral perfusion may be encountered in an artificial cardiopulmonary bypass used in cardiac surgery, which is exceptional in physiological conditions. The authors report on a 37-year-old woman with Takayasu's arteritis (TA) who had been suffering from progressive visual loss and recurrent seizures. Ocular findings of chronic ischemia and multiple, subcortical, high-signal lesions in magnetic resonance (MR) imaging were indicative of significant hemodynamic impairment. MR angiography showed the complete occlusion of the innominate artery, the left common carotid artery (CCA), and the subclavian artery from the orifice of the aortic arch. The patient's transcranial Doppler (TCD) waveform was flat throughout all segments of the intracranial arteries. Intravenous acetazolamide injection confirmed the severe impairment of vasoreactivity. After a bypass graft from the aorta to the left CCA, flow velocity and pulsatility were dramatically increased without postoperative complications. A nonpulsatile cerebral perfusion indicates severe hemodynamic impairment and is partially reversible by a surgical bypass graft. TCD seems to be useful to detect "high-risk" patients and to follow up in TA.
Authors:
Yong-Seok Lee; Byung-Woo Yoon; Jae-Kyu Roh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  13     ISSN:  1051-2284     ISO Abbreviation:  J Neuroimaging     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-30     Completed Date:  2003-05-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-71     Citation Subset:  IM    
Affiliation:
Seoul Municipal Boramae Hospital.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Ischemia / diagnosis*,  etiology,  surgery
Cerebral Angiography
Cerebral Revascularization
Female
Humans
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Takayasu Arteritis / complications*,  surgery
Ultrasonography, Doppler, Transcranial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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