| Nonpharmacological treatment options for epilepsy. | |
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MedLine Citation:
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PMID: 16114176 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Approximately one third of children with epilepsy have persistent seizures despite trials of multiple antiepileptic medications. For some of these patients, epilepsy surgery may provide freedom from seizures. However, in many cases, epilepsy surgery is not a viable treatment option. Nonpharmacological approaches are a useful adjunct to help manage seizures in these children. This review examines the role of vagus nerve stimulation, the ketogenic diet, and various forms of EEG biofeedback therapy in children with intractable epilepsy. Although the mechanism of action is not known precisely for any of these adjunctive therapies, they add an important and evolving dimension to the management of difficult to control epilepsy in children. In addition, pyridoxine-dependent seizures are discussed as an example of an etiology of refractory seizures that responds well to replacement therapy. |
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Authors:
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Raj D Sheth; Carl E Stafstrom; David Hsu |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in pediatric neurology Volume: 12 ISSN: 1071-9091 ISO Abbreviation: Semin Pediatr Neurol Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-08-23 Completed Date: 2005-10-19 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 9441351 Medline TA: Semin Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 106-13 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Wisconsin, Madison, Madison, WI 53792-5132, USA. sheth@neurology.wisc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Allylamine
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administration & dosage,
analogs & derivatives Biofeedback, Psychology / methods* Diet Therapy / methods* Drug Combinations Electric Stimulation / methods* Electroencephalography / methods Epilepsy / classification, therapy* Humans Meperidine / administration & dosage, analogs & derivatives Neurosurgery / methods* Pyridoxine / therapeutic use Vagus Nerve / physiopathology, radiation effects |
| Chemical | |
Reg. No./Substance:
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0/Drug Combinations; 107-11-9/Allylamine; 57-42-1/Meperidine; 65-23-6/Pyridoxine; 81605-86-9/Ketogin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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