Document Detail

Nonpharmacologic strategies: the evolving story of ablation and hybrid therapy.
MedLine Citation:
PMID:  18790111     Owner:  NLM     Status:  MEDLINE    
Technologic advancements have resulted in the more widespread use of catheter ablation to restore sinus rhythm in patients with atrial fibrillation (AF) and elicit improvement in symptoms, quality of life, and prognosis. However, the effectiveness of this procedure to prevent the occurrence of heart failure and stroke while reducing mortality has yet to be proved in major clinical trials. Factors influencing the results of ablation and possibly obfuscating the interpretation of data from early studies include variations in center experience and operator skill, the definition of procedural success, and follow-up interval and duration, as well as the complexity and heterogeneity of AF itself. Upcoming trials that will examine outcomes after catheter ablation and pharmacologic strategies from the end points of heart failure, stroke, and mortality are anticipated to yield more definitive conclusions about ablation efficacy.
Andre d'Avila; Jeremy N Ruskin
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of cardiology     Volume:  102     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-15     Completed Date:  2008-11-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  20H-24H     Citation Subset:  AIM; IM    
Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
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MeSH Terms
Atrial Fibrillation / surgery*
Catheter Ablation*
Clinical Competence
Clinical Trials as Topic
Laser Therapy
Ultrasonic Therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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