| Nonnecrobiotic Necrobiotic Xanthogranuloma as an Initial Manifestation of Paraproteinemia and Small Lymphocytic Lymphoma in a Patient With Sjögren Syndrome. | |
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MedLine Citation:
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PMID: 22042261 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We report a unique case of periocular nonnecrobiotic necrobiotic xanthogranuloma in a 52-year-old white woman with Sjögren syndrome who was subsequently found to have an immunoglobulin G paraproteinemia and coexisting small lymphocytic lymphoma. Therapy with fludarabine, cytoxan, and rituximab (FCR) resulted in a dramatic resolution of her sicca symptoms and periocular xanthogranulomas. This case further illustrates the association of hematolymphoid disorders with cutaneous xanthogranulomatous disease and the importance of additional appropriate laboratory and radiologic investigation for the accurate diagnosis of an underlying malignancy. |
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Authors:
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Mojdeh Naghashpour; Reza Setoodeh; Lynn Moscinski; Gregoire Bergier; Timothy McCardle; Frank Glass; Lubomir Sokol |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-29 |
Journal Detail:
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Title: The American Journal of dermatopathology Volume: - ISSN: 1533-0311 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-11-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7911005 Medline TA: Am J Dermatopathol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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From the *Department of Hematopathology, H. Lee Moffitt Cancer Center; †Department of Pathology and Cell Biology, University of South Florida; ‡Department of Hematopathology, H. Lee Moffitt Cancer Center; §Gulfcoast Oncology Associates; ‖Department of Dermatology, University of South Florida; and ¶Department of Malignant Hematology, H. Lee Moffitt Cancer Center. |
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