Document Detail


Nonlinearity in the relationship between bone lead concentrations and CBLI for lead smelter employees.
MedLine Citation:
PMID:  23152131     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
494 smelter employees from New Brunswick participated in a bone lead survey conducted by McMaster University in 2008, using the four element "clover-leaf" geometry germanium detector system. The employees were measured at two different bone sites, tibia and calcaneus, each measurement lasting 30 minutes. Scattered photons, including Pb X-rays, were collected by the germanium detectors located behind the (109)Cd source. A strong positive correlation was observed between tibia and calcaneus lead concentrations. Having been provided with blood lead levels, a cumulative blood lead index (CBLI) was generated. The employees were classified into four groups based on their date of hire, and their CBLI levels were compared to their tibia and calcaneus lead concentrations in the different groups. The slopes of bone Pb versus CBLI varied amongst groups, with those hired earliest showing the steepest slopes. This could be taken to imply a non-linearity in the uptake of Pb by bone from blood. In this paper, the association of the bone lead concentrations versus CBLI has been expressed by a polynomial function for the whole group of employees.
Authors:
Sepideh Behinaein; David R Chettle; Lesley M Egden; Fiona E McNeill; Geoff Norman; Norbert Richard; Susan Stever
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-14
Journal Detail:
Title:  Journal of environmental monitoring : JEM     Volume:  -     ISSN:  1464-0333     ISO Abbreviation:  J Environ Monit     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100968688     Medline TA:  J Environ Monit     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario, CanadaL8S 4K1. behinas@mcmaster.ca.
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